(3-Phenyl-2-propenyl)triphenylphosphonium bromide

(3-Phenyl-2-propenyl)triphenylphosphonium bromide - Names and Identifiers

Name	Cinnamyl triphenylphosphonium bromide
Synonyms	Cinnamyltriphenylphosphonium bromide CINNAMYLTRIPHENYLPHOSPHONIUM BROMIDE Cinnamyl triphenylphosphonium bromide Triphenyl(3-phenyl-2-propenyl)phosphonium bromide (3-Phenyl-2-propenyl)triphenylphosphonium bromide 3-PHENYL-2-PROPEN-1-YLTRIPHENYLPHOSPHONIUM BROMIDE triphenyl[(2E)-3-phenylprop-2-en-1-yl]phosphonium bromide
CAS	7310-74-9
InChI	InChI=1/C27H24P.BrH/c1-5-14-24(15-6-1)16-13-23-28(25-17-7-2-8-18-25,26-19-9-3-10-20-26)27-21-11-4-12-22-27;/h1-22H,23H2;1H/q+1;/p-1/b16-13+

(3-Phenyl-2-propenyl)triphenylphosphonium bromide - Physico-chemical Properties

Molecular Formula	C27H24BrP
Molar Mass	459.36
Melting Point	254-258 °C
Solubility	very faint turbidity in Methanol
Appearance	solid
Color	White to Almost white
BRN	4172462
Storage Condition	2-8℃
Sensitive	Hygroscopic
MDL	MFCD00040767

(3-Phenyl-2-propenyl)triphenylphosphonium bromide - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S37/39 - Wear suitable gloves and eye/face protection S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

(3-Phenyl-2-propenyl)triphenylphosphonium bromide - Introduction

Cinnamyl triphenylphosphonium bromide is an organic compound with the chemical formula C6H5C(O)CH2PPh3Br. The following is a description of the nature, use, preparation and safety information of Cinnamyl triphenylphosphonium bromide:

Nature:
-Appearance: Cinnamyl triphenylphosphonium bromide is a white crystalline solid.
-Solubility: It can be dissolved in organic solvents, such as chloroform, methanol and ethanol.
-Thermal stability: Cinnamyl the triphenylphosphonium bromide is relatively stable at room temperature, it may decompose at high temperatures.

Use:
-Catalyst: Cinnamyl triphenylphosphonium bromide can be used as catalysts in organic synthesis, especially in cross-coupling reactions, such as Suzuki coupling reactions.
-Organic synthesis intermediate: It can be used as an intermediate for the synthesis of other compounds, such as organic lithium reagents and Grignard reagents.

Preparation Method:
Cinnamyl triphenylphosphonium bromide can be prepared by the following reactions:
1. A Vickers reagent (triphenylphosphine) is reacted with a bromoalkyl compound to generate a bromoalkyl triphenylphosphine compound.
2. cinnamic acid reacts with a bromoalkyl triphenylphosphine compound to generate a Cinnamyl triphenylphosphonium bromide.

Safety Information:
- Cinnamyl triphenylphosphonium bromide are potentially harmful to the environment, care should be taken to prevent them from entering the water and soil.
-Wear appropriate personal protective equipment such as chemical goggles, protective gloves, and protective clothing during use or handling.
-During storage and transportation, Cinnamyl triphenylphosphonium bromide should be kept away from ignition and oxidizing agents.
-Avoid inhaling its dust or contact with skin and eyes during use. In case of contact, rinse immediately with plenty of water and seek medical help.

Last Update：2024-04-10 22:29:15